In 1500 BCE trade routes for drugs were already well established between the Mediterranean and the Levant [105]. Inevitably, information and new discoveries also changed hands and huge similarities are evident in records of the drugs used by major civilisations around this time including Mesopotamia, Egypt and India [105].
Similarities in the ways specific plants are used across a diverse range of cultures is evidence of primitive human-plant relationships [105].
Hibiscus rosa-sinensis has been used as a hot-water extract to treat menstrual problems and to regulate fertitily amongst primitive peoples in all of the following regions [105]:
Scratchpads developed and conceived by (alphabetical):
Ed Baker,
Katherine Bouton
Alice Heaton
Dimitris Koureas,
Laurence Livermore,
Dave Roberts,
Simon Rycroft,
Ben Scott,
Vince Smith